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Lipids as Trans-Acting Effectors for α-Synuclein in the Pathogenesis of Parkinson’s Disease

Aggregation of α-synuclein (αSyn) plays a central role in the pathogenesis of Parkinson’s disease (PD) and dementia with Lewy bodies (DLB). Lewy bodies (LBs) and Lewy neurites, which consist mainly of aggregated αSyn, are widely observed in the affected regions of patient brains. Except for some fam...

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Veröffentlicht in:Front Neurosci
Hauptverfasser: Ikenaka, Kensuke, Suzuki, Mari, Mochizuki, Hideki, Nagai, Yoshitaka
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2019
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6619337/
https://ncbi.nlm.nih.gov/pubmed/31333408
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnins.2019.00693
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