Proteostasis of α-Synuclein and Its Role in the Pathogenesis of Parkinson’s Disease

Aggregation of α-Synuclein, possibly caused by disturbance of proteostasis, has been identified as a common pathological feature of Parkinson’s disease (PD). However, the initiating events of aggregation have not been fully illustrated, and this knowledge may be critical to understanding the disease...

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Udgivet i:Front Cell Neurosci
Main Authors: Han, Deqiang, Zheng, Wei, Wang, Xueyao, Chen, Zhiguo
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2020
Fag:
Cellular Neuroscience
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7075857/
https://ncbi.nlm.nih.gov/pubmed/32210767
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fncel.2020.00045
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