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Parkinson’s disease is a type of amyloidosis featuring accumulation of amyloid fibrils of α-synuclein
Many neurodegenerative diseases are characterized by the accumulation of abnormal protein aggregates in the brain. In Parkinson’s disease (PD), α-synuclein (α-syn) forms such aggregates called Lewy bodies (LBs). Recently, it has been reported that aggregates of α-syn with a cross-β structure are cap...
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| Publicado en: | Proc Natl Acad Sci U S A |
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| Autores principales: | , , , , , , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
National Academy of Sciences
2019
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6731630/ https://ncbi.nlm.nih.gov/pubmed/31427526 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1906124116 |
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