Parkinson’s disease is a type of amyloidosis featuring accumulation of amyloid fibrils of α-synuclein

Many neurodegenerative diseases are characterized by the accumulation of abnormal protein aggregates in the brain. In Parkinson’s disease (PD), α-synuclein (α-syn) forms such aggregates called Lewy bodies (LBs). Recently, it has been reported that aggregates of α-syn with a cross-β structure are cap...

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Dettagli Bibliografici
Pubblicato in:Proc Natl Acad Sci U S A
Autori principali: Araki, Katsuya, Yagi, Naoto, Aoyama, Koki, Choong, Chi-Jing, Hayakawa, Hideki, Fujimura, Harutoshi, Nagai, Yoshitaka, Goto, Yuji, Mochizuki, Hideki
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2019
Soggetti:
Biological Sciences
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6731630/
https://ncbi.nlm.nih.gov/pubmed/31427526
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1906124116
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