Optimized sonoreactor for accelerative amyloid-fibril assays through enhancement of primary nucleation and fragmentation

Ultrasonication to supersaturated protein solutions forcibly forms amyloid fibrils, thereby allowing the early-stage diagnosis for amyloidoses. Previously, we constructed a high-throughput sonoreactor to investigate features of the amyloid-fibril nucleation. Although the instrument substantiated the...

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Vydáno v:Ultrason Sonochem
Hlavní autoři: Nakajima, Kichitaro, Noi, Kentaro, Yamaguchi, Keiichi, So, Masatomo, Ikenaka, Kensuke, Mochizuki, Hideki, Ogi, Hirotsugu, Goto, Yuji
Médium: Artigo
Jazyk:Inglês
Vydáno: Elsevier 2021
Témata:
Original Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7994783/
https://ncbi.nlm.nih.gov/pubmed/33770746
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ultsonch.2021.105508
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