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Nucleus factory on cavitation bubble for amyloid β fibril

Structural evolution from monomer to fibril of amyloid β peptide is related to pathogenic mechanism of Alzheimer disease, and its acceleration is a long-running problem in drug development. This study reveals that ultrasonic cavitation bubbles behave as catalysts for nucleation of the peptide: The n...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Nakajima, Kichitaro, Ogi, Hirotsugu, Adachi, Kanta, Noi, Kentaro, Hirao, Masahiko, Yagi, Hisashi, Goto, Yuji
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4766559/
https://ncbi.nlm.nih.gov/pubmed/26912021
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep22015
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