A carregar...
The BRISC deubiquitinating enzyme complex limits hematopoietic stem cell expansion by regulating JAK2 K63-ubiquitination
Hematopoietic stem cell (HSC) homeostasis is controlled by cytokine receptor–mediated Janus kinase 2 (JAK2) signaling. We previously found that JAK2 is promptly ubiquitinated upon cytokine stimulation. Whether a competing JAK2 deubiquitination activity exists is unknown. LNK is an essential adaptor...
Na minha lista:
| Publicado no: | Blood |
|---|---|
| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society of Hematology
2019
|
| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6450430/ https://ncbi.nlm.nih.gov/pubmed/30755420 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2018-10-877563 |
| Tags: |
Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!
|