A Novel BRISC-SHMT Complex Deubiquitinates IFNAR1 and Regulates Interferon Responses

Lysine63-linked ubiquitin (K63-Ub) chains represent a particular ubiquitin topology that mediates proteasome-independent signaling events. The deubiquitinating enzyme (DUB) BRCC36 segregates into distinct nuclear and cytoplasmic complexes that are specific for K63-Ub hydrolysis. RAP80 targets the fi...

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Hlavní autoři: Zheng, Hui, Gupta, Vibhor, Patterson-Fortin, Jeffrey, Bhattacharya, Sabyasachi, Katlinski, Kanstantsin, Wu, Junmin, Varghese, Bentley, Carbone, Christopher J., Aressy, Bernadette, Fuchs, Serge Y., Greenberg, Roger A.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2013
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3813903/
https://ncbi.nlm.nih.gov/pubmed/24075985
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2013.08.025
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