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Specificity of the BRISC Deubiquitinating Enzyme Is Not Due to Selective Binding to Lys(63)-linked Polyubiquitin
BRISC (Brcc36-containing isopeptidase complex) is a four-subunit deubiquitinating (DUB) enzyme that has a catalytic subunit, called Brcc36, that is a member of the JAMM/MPN(+) family of zinc metalloproteases. A notable feature of BRISC is its high specificity for cleaving Lys(63)-linked polyubiquiti...
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| Auteurs principaux: | , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
American Society for Biochemistry and Molecular Biology
2010
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2856240/ https://ncbi.nlm.nih.gov/pubmed/20032457 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.059667 |
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