Enhanced Pharmacological Ascorbate Oxidation Radiosensitizes Pancreatic Cancer

Pharmacologic ascorbate (P-AscH(–)) is emerging as a promising adjuvant for advanced pancreatic cancer. P-AscH(–)generates hydrogen peroxide (H(2)O(2)), leading to selective cancer cell cytotoxicity. Catalytic manganoporphyrins, such as MnT4MPyP, can increase the rate of oxidation of P-AscH(–), ther...

Descrición completa

Gardado en:
Detalles Bibliográficos
Publicado en:Radiat Res
Main Authors: Alexander, Matthew S., O’Leary, Brianne R., Wilkes, Justin G., Gibson, Adrienne R., Wagner, Brett A., Du, Juan, Sarsour, Ehab, Hwang, Rosa F., Buettner, Garry R., Cullen, Joseph J.
Formato: Artigo
Idioma:Inglês
Publicado: 2018
Assuntos:
Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6441967/
https://ncbi.nlm.nih.gov/pubmed/30376411
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1667/RR15189.1
Tags: Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!

Títulos similares