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Pharmacological ascorbate and ionizing radiation (IR) increase labile iron in pancreatic cancer()

Labile iron, i.e. iron that is weakly bound and is relatively unrestricted in its redox activity, has been implicated in both the pathogenesis as well as treatment of cancer. Two cancer treatments where labile iron may contribute to their mechanism of action are pharmacological ascorbate and ionizin...

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Detalhes bibliográficos
Main Authors: Moser, Justin C., Rawal, Malvika, Wagner, Brett A., Du, Juan, Cullen, Joseph J., Buettner, Garry R.
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3881203/
https://ncbi.nlm.nih.gov/pubmed/24396727
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.redox.2013.11.005
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