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The Role of Labile Iron in the Toxicity of Pharmacological Ascorbate
Pharmacological ascorbate has been shown to induce toxicity in a wide range of cancer cell lines; using animal models pharmacological ascorbate has shown promise for use in cancer treatment. At pharmacological concentrations the oxidation of ascorbate produces a high flux of H(2)O(2) via the formati...
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Publicado no: | Free Radic Biol Med |
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Main Authors: | , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2015
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4739508/ https://ncbi.nlm.nih.gov/pubmed/25857216 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.freeradbiomed.2015.03.033 |
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