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The Role of Labile Iron in the Toxicity of Pharmacological Ascorbate

Pharmacological ascorbate has been shown to induce toxicity in a wide range of cancer cell lines; using animal models pharmacological ascorbate has shown promise for use in cancer treatment. At pharmacological concentrations the oxidation of ascorbate produces a high flux of H(2)O(2) via the formati...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Free Radic Biol Med
Päätekijät: Du, Juan, Wagner, Brett A., Buettner, Garry R., Cullen, Joseph J.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2015
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4739508/
https://ncbi.nlm.nih.gov/pubmed/25857216
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.freeradbiomed.2015.03.033
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