Catalase Modulates the Radio-Sensitization of Pancreatic Cancer Cells by Pharmacological Ascorbate

Pancreatic cancer cells (PDACs) are more susceptible to an oxidative insult than normal cells, resulting in greater cytotoxicity upon exposure to agents that increase pro-oxidant levels. Pharmacological ascorbate (P-AscH(−)), i.e., large amounts given intravenously (IV), generates significant fluxes...

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Publicado en:Antioxidants (Basel)
Autores principales: Du, Juan, Carroll, Rory S., Steers, Garett J., Wagner, Brett A., O’Leary, Brianne R., Jensen, Chris S., Buettner, Garry R., Cullen, Joseph J.
Formato: Artigo
Lenguaje:Inglês
Publicado: MDPI 2021
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC8073689/
https://ncbi.nlm.nih.gov/pubmed/33923601
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/antiox10040614
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