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Catalase Modulates the Radio-Sensitization of Pancreatic Cancer Cells by Pharmacological Ascorbate

Pancreatic cancer cells (PDACs) are more susceptible to an oxidative insult than normal cells, resulting in greater cytotoxicity upon exposure to agents that increase pro-oxidant levels. Pharmacological ascorbate (P-AscH(−)), i.e., large amounts given intravenously (IV), generates significant fluxes...

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Detalhes bibliográficos
Publicado no:Antioxidants (Basel)
Main Authors: Du, Juan, Carroll, Rory S., Steers, Garett J., Wagner, Brett A., O’Leary, Brianne R., Jensen, Chris S., Buettner, Garry R., Cullen, Joseph J.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8073689/
https://ncbi.nlm.nih.gov/pubmed/33923601
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/antiox10040614
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