Targeting Processive Transcription Elongation Via SEC Disruption for Myc Induced Cancer Therapy

The Super Elongation Complex (SEC) is required for robust and productive transcription through release of RNA Polymerase II (Pol II) with its P-TEFb module and promoting transcriptional processivity with its ELL2 subunit. Malfunction of SEC contributes to multiple human diseases including cancer. He...

詳細記述

保存先:
書誌詳細
出版年:Cell
主要な著者: Liang, Kaiwei, Smith, Edwin R., Aoi, Yuki, Stoltz, Kristen L., Katagi, Hiroaki, Woodfin, Ashley R., Rendleman, Emily J., Marshall, Stacy A., Murray, David C., Wang, Lu, Ozark, Patrick A., Mishra, Rama K., Hashizume, Rintaro, Schiltz, Gary E., Shilatifard, Ali
フォーマット: Artigo
言語:Inglês
出版事項: 2018
主題:
Article
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6422358/
https://ncbi.nlm.nih.gov/pubmed/30340042
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2018.09.027
タグ: タグ追加
タグなし, このレコードへの初めてのタグを付けませんか!

類似資料