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Excess growth hormone suppresses DNA damage repair in epithelial cells
Growth hormone (GH) decreases with age, and GH therapy has been advocated by some to sustain lean muscle mass and vigor in aging patients and advocated by athletes to enhance performance. Environmental insults and aging lead to DNA damage, which — if unrepaired — results in chromosomal instability a...
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| Publicado no: | JCI Insight |
|---|---|
| Main Authors: | , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Clinical Investigation
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6413789/ https://ncbi.nlm.nih.gov/pubmed/30728323 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.125762 |
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