Growth hormone is permissive for neoplastic colon growth

Growth hormone (GH) excess in acromegaly is associated with increased precancerous colon polyps and soft tissue adenomas, whereas short-stature humans harboring an inactivating GH receptor mutation do not develop cancer. We show that locally expressed colon GH is abundant in conditions predisposing...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Chesnokova, Vera, Zonis, Svetlana, Zhou, Cuiqi, Recouvreux, Maria Victoria, Ben-Shlomo, Anat, Araki, Takako, Barrett, Robert, Workman, Michael, Wawrowsky, Kolja, Ljubimov, Vladimir A., Uhart, Magdalena, Melmed, Shlomo
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2016
Assuntos:
PNAS Plus
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4988562/
https://ncbi.nlm.nih.gov/pubmed/27226307
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1600561113
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados