p21(Cip1) restrains pituitary tumor growth

As commonly encountered, pituitary adenomas are invariably benign. We therefore studied protective pituitary proliferative mechanisms. Pituitary tumor transforming gene (Pttg) deletion results in pituitary p21 induction and abrogates tumor development in Rb(+/−)Pttg(−/−) mice. p21 disruption restore...

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Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Chesnokova, Vera, Zonis, Svetlana, Kovacs, Kalman, Ben-Shlomo, Anat, Wawrowsky, Kolja, Bannykh, Serguei, Melmed, Shlomo
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: National Academy of Sciences 2008
Gaiak:
Biological Sciences
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2577704/
https://ncbi.nlm.nih.gov/pubmed/18981426
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0804810105
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