Excess growth hormone suppresses DNA damage repair in epithelial cells

Growth hormone (GH) decreases with age, and GH therapy has been advocated by some to sustain lean muscle mass and vigor in aging patients and advocated by athletes to enhance performance. Environmental insults and aging lead to DNA damage, which — if unrepaired — results in chromosomal instability a...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:JCI Insight
Egile Nagusiak: Chesnokova, Vera, Zonis, Svetlana, Barrett, Robert, Kameda, Hiraku, Wawrowsky, Kolja, Ben-Shlomo, Anat, Yamamoto, Masaaki, Gleeson, John, Bresee, Catherine, Gorbunova, Vera, Melmed, Shlomo
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Clinical Investigation 2019
Gaiak:
Research Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6413789/
https://ncbi.nlm.nih.gov/pubmed/30728323
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.125762
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