Excess growth hormone suppresses DNA damage repair in epithelial cells

Growth hormone (GH) decreases with age, and GH therapy has been advocated by some to sustain lean muscle mass and vigor in aging patients and advocated by athletes to enhance performance. Environmental insults and aging lead to DNA damage, which — if unrepaired — results in chromosomal instability a...

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Detaylı Bibliyografya
Yayımlandı:JCI Insight
Asıl Yazarlar: Chesnokova, Vera, Zonis, Svetlana, Barrett, Robert, Kameda, Hiraku, Wawrowsky, Kolja, Ben-Shlomo, Anat, Yamamoto, Masaaki, Gleeson, John, Bresee, Catherine, Gorbunova, Vera, Melmed, Shlomo
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Clinical Investigation 2019
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6413789/
https://ncbi.nlm.nih.gov/pubmed/30728323
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.125762
Etiketler: Etiketle
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