Acarbose improves health and lifespan in aging HET3 mice

To follow‐up on our previous report that acarbose (ACA), a drug that blocks postprandial glucose spikes, increases mouse lifespan, we studied ACA at three doses: 400, 1,000 (the original dose), and 2,500 ppm, using genetically heterogeneous mice at three sites. Each dose led to a significant change...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:Aging Cell
Main Authors: Harrison, David E., Strong, Randy, Alavez, Silvestre, Astle, Clinton Michael, DiGiovanni, John, Fernandez, Elizabeth, Flurkey, Kevin, Garratt, Michael, Gelfond, Jonathan A. L., Javors, Martin A., Levi, Moshe, Lithgow, Gordon J., Macchiarini, Francesca, Nelson, James F., Sukoff Rizzo, Stacey J., Slaga, Thomas J., Stearns, Tim, Wilkinson, John Erby, Miller, Richard A.
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley and Sons Inc. 2019
Fag:
Original Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6413665/
https://ncbi.nlm.nih.gov/pubmed/30688027
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.12898
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker