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The chromatin accessibility landscape of primary human cancers

We present the genome-wide chromatin accessibility profiles of 410 tumor samples spanning 23 cancer types from The Cancer Genome Atlas. We identify 562,709 transposase-accessible DNA elements that substantially extend the compendium of known cis-regulatory elements. Integration of ATAC-seq with TCGA...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Science
Egile Nagusiak: Corces, M. Ryan, Granja, Jeffrey M., Shams, Shadi, Louie, Bryan H., Seoane, Jose A., Zhou, Wanding, Silva, Tiago C., Groeneveld, Clarice, Wong, Christopher K., Cho, Seung Woo, Satpathy, Ansuman T., Mumbach, Maxwell R., Hoadley, Katherine A., Robertson, A. Gordon, Sheffield, Nathan C., Felau, Ina, Castro, Mauro A.A., Berman, Benjamin P., Staudt, Louis M., Zenklusen, Jean C., Laird, Peter W., Curtis, Christina, Greenleaf, William J., Chang, Howard Y.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2018
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6408149/
https://ncbi.nlm.nih.gov/pubmed/30361341
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.aav1898
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