Insulin deficiency and intranasal insulin alter brain mitochondrial function: a potential factor for dementia in diabetes

Despite the strong association between diabetes and dementia, it remains to be fully elucidated how insulin deficiency adversely affects brain functions. We show that insulin deficiency in streptozotocin-induced diabetic mice decreased mitochondrial ATP production and/or citrate synthase and cytochr...

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Detaylı Bibliyografya
Yayımlandı:FASEB J
Asıl Yazarlar: Ruegsegger, Gregory N., Manjunatha, Shankarappa, Summer, Priska, Gopala, Srinivas, Zabeilski, Piotr, Dasari, Surendra, Vanderboom, Patrick M., Lanza, Ian R., Klaus, Katherine A., Nair, K. Sreekumaran
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Federation of American Societies for Experimental Biology 2019
Konular:
Research
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6404590/
https://ncbi.nlm.nih.gov/pubmed/30676773
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.201802043R
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