Altered Skeletal Muscle Mitochondrial Proteome As the Basis of Disruption of Mitochondrial Function in Diabetic Mice

Insulin plays pivotal role in cellular fuel metabolism in skeletal muscle. Despite being the primary site of energy metabolism, the underlying mechanism on how insulin deficiency deranges skeletal muscle mitochondrial physiology remains to be fully understood. Here we report an important link betwee...

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Publicat a:Diabetes
Autors principals: Zabielski, Piotr, Lanza, Ian R., Gopala, Srinivas, Holtz Heppelmann, Carrie J., Bergen, H. Robert, Dasari, Surendra, Nair, K. Sreekumaran
Format: Artigo
Idioma:Inglês
Publicat: American Diabetes Association 2016
Matèries:
Metabolism
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4764144/
https://ncbi.nlm.nih.gov/pubmed/26718503
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db15-0823
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