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Altered mitochondrial function in insulin-deficient and insulin-resistant states

Diabetes profoundly alters fuel metabolism; both insulin deficiency and insulin resistance are characterized by inefficient mitochondrial coupling and excessive production of reactive oxygen species (ROS) despite their association with normal to high oxygen consumption. Altered mitochondrial functio...

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Bibliografiske detaljer
Udgivet i:J Clin Invest
Main Authors: Ruegsegger, Gregory N., Creo, Ana L., Cortes, Tiffany M., Dasari, Surendra, Nair, K. Sreekumaran
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Clinical Investigation 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6118582/
https://ncbi.nlm.nih.gov/pubmed/30168804
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI120843
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