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Mitochondrial DNA Alterations and Reduced Mitochondrial Function in Aging

Oxidative damage to mitochondrial DNA increases with aging. This damage has the potential to affect mitochondrial DNA replication and transcription which could alter the abundance or functionality of mitochondrial proteins. This review describes mitochondrial DNA alterations and changes in mitochond...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Hebert, Sadie L., Lanza, Ian R., Nair, K. Sreekumaran
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2010
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2910809/
https://ncbi.nlm.nih.gov/pubmed/20307565
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mad.2010.03.007
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