Molecular basis for AU-rich element recognition and dimerization by the HuR C-terminal RRM

Human antigen R (HuR) is a key regulator of cellular mRNAs containing adenylate/uridylate–rich elements (AU-rich elements; AREs). These are a major class of cis elements within 3′ untranslated regions, targeting these mRNAs for rapid degradation. HuR contains three RNA recognition motifs (RRMs): a t...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Proc Natl Acad Sci U S A
Egile Nagusiak: Ripin, Nina, Boudet, Julien, Duszczyk, Malgorzata M., Hinniger, Alexandra, Faller, Michael, Krepl, Miroslav, Gadi, Abhilash, Schneider, Robert J., Šponer, Jiří, Meisner-Kober, Nicole C., Allain, Frédéric H.-T.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: National Academy of Sciences 2019
Gaiak:
PNAS Plus
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6386705/
https://ncbi.nlm.nih.gov/pubmed/30718402
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1808696116
Etiketak: Etiketa erantsi
Etiketarik gabe, Izan zaitez lehena erregistro honi etiketa jartzen!

Antzeko izenburuak