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Structural study of the Fox-1 RRM protein hydration reveals a role for key water molecules in RRM-RNA recognition
The Fox-1 RNA recognition motif (RRM) domain is an important member of the RRM protein family. We report a 1.8 Å X-ray structure of the free Fox-1 containing six distinct monomers. We use this and the nuclear magnetic resonance (NMR) structure of the Fox-1 protein/RNA complex for molecular dynamics...
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| Publicado no: | Nucleic Acids Res |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5737849/ https://ncbi.nlm.nih.gov/pubmed/28505313 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkx418 |
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