CX3CR1-deficient microglia shows impaired signalling of the transcription factor NRF2: Implications in tauopathies

TAU protein aggregation is the main characteristic of neurodegenerative diseases known as tauopathies. Low-grade chronic inflammation is also another hallmark that indicates crosstalk between damaged neurons and glial cells. Previously, we have demonstrated that neurons overexpressing TAU(P301L) rel...

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Detaylı Bibliyografya
Yayımlandı:Redox Biol
Asıl Yazarlar: Castro-Sánchez, Sara, García-Yagüe, Ángel J., Kügler, Sebastian, Lastres-Becker, Isabel
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Elsevier 2019
Konular:
Research Paper
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6375000/
https://ncbi.nlm.nih.gov/pubmed/30769286
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.redox.2019.101118
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