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Cx3cr1-deficient microglia exhibit a premature aging transcriptome

CX3CR1, one of the highest expressed genes in microglia in mice and humans, is implicated in numerous microglial functions. However, the molecular mechanisms underlying Cx3cr1 signaling are not well understood. Here, we analyzed transcriptomes of Cx3cr1-deficient microglia under varying conditions b...

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Foilsithe in:Life Sci Alliance
Main Authors: Gyoneva, Stefka, Hosur, Raghavendra, Gosselin, David, Zhang, Baohong, Ouyang, Zhengyu, Cotleur, Anne C, Peterson, Michael, Allaire, Norm, Challa, Ravi, Cullen, Patrick, Roberts, Chris, Miao, Kelly, Reynolds, Taylor L, Glass, Christopher K, Burkly, Linda, Ransohoff, Richard M
Formáid: Artigo
Teanga:Inglês
Foilsithe: Life Science Alliance LLC 2019
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6892408/
https://ncbi.nlm.nih.gov/pubmed/31792059
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.26508/lsa.201900453
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