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Pharmacological targeting of GSK-3 and NRF2 provides neuroprotection in a preclinical model of tauopathy
Tauopathies are a group of neurodegenerative disorders where TAU protein is presented as aggregates or is abnormally phosphorylated, leading to alterations of axonal transport, neuronal death and neuroinflammation. Currently, there is no treatment to slow progression of these diseases. Here, we have...
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| 出版年: | Redox Biol |
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| 主要な著者: | , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Elsevier
2017
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5681345/ https://ncbi.nlm.nih.gov/pubmed/29121589 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.redox.2017.10.010 |
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