CX3CR1-deficient microglia shows impaired signalling of the transcription factor NRF2: Implications in tauopathies

TAU protein aggregation is the main characteristic of neurodegenerative diseases known as tauopathies. Low-grade chronic inflammation is also another hallmark that indicates crosstalk between damaged neurons and glial cells. Previously, we have demonstrated that neurons overexpressing TAU(P301L) rel...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Redox Biol
Egile Nagusiak: Castro-Sánchez, Sara, García-Yagüe, Ángel J., Kügler, Sebastian, Lastres-Becker, Isabel
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Elsevier 2019
Gaiak:
Research Paper
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6375000/
https://ncbi.nlm.nih.gov/pubmed/30769286
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.redox.2019.101118
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