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CX3CR1 deficiency suppresses activation and neurotoxicity of microglia/macrophage in experimental ischemic stroke

BACKGROUND: Chemokine (C-X3-C motif) ligand 1 (CX3CL1)/ CX3C chemokine receptor 1 (CX3CR1) signaling is important in modulating the communication between neurons and resident microglia/migrated macrophages in the central nervous system (CNS). Although CX3CR1 deficiency is associated with an improved...

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Detalhes bibliográficos
Main Authors: Tang, Zhiwei, Gan, Yan, Liu, Qiang, Yin, Jun-Xiang, Liu, Qingwei, Shi, Jiong, Shi, Fu-Dong
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3942808/
https://ncbi.nlm.nih.gov/pubmed/24490760
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-2094-11-26
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