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Suppressed pro-inflammatory response of microglia in CX3CR1 knockout mice
Neuronal fractalkine acts via its receptor, CX3CR1, on microglia to regulate neuroinflammation. Conflicting results have been reported in studies employing CX3CR1 deficient (Cx3cr1(-/-)) mice. Here, compared to wild-type, endotoxin-treated neuron-glial Cx3cr1(-/-) cultures produced less TNF-α, nitri...
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| 主要な著者: | , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2013
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3702048/ https://ncbi.nlm.nih.gov/pubmed/23499256 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jneuroim.2013.02.008 |
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