Suppressed pro-inflammatory response of microglia in CX3CR1 knockout mice

Neuronal fractalkine acts via its receptor, CX3CR1, on microglia to regulate neuroinflammation. Conflicting results have been reported in studies employing CX3CR1 deficient (Cx3cr1(-/-)) mice. Here, compared to wild-type, endotoxin-treated neuron-glial Cx3cr1(-/-) cultures produced less TNF-α, nitri...

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Detaylı Bibliyografya
Asıl Yazarlar: Mattison, Hayley A., Nie, Hui, Gao, Huiming, Zhou, Hui, Hong, Jau-Shyong, Zhang, Jing
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2013
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3702048/
https://ncbi.nlm.nih.gov/pubmed/23499256
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jneuroim.2013.02.008
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