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Suppressed pro-inflammatory response of microglia in CX3CR1 knockout mice
Neuronal fractalkine acts via its receptor, CX3CR1, on microglia to regulate neuroinflammation. Conflicting results have been reported in studies employing CX3CR1 deficient (Cx3cr1(-/-)) mice. Here, compared to wild-type, endotoxin-treated neuron-glial Cx3cr1(-/-) cultures produced less TNF-α, nitri...
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| Autori principali: | , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2013
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3702048/ https://ncbi.nlm.nih.gov/pubmed/23499256 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jneuroim.2013.02.008 |
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