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Modeling anti-CD19 CAR T cell therapy in humanized mice with human immunity and autologous leukemia
BACKGROUND: Adoptive immunotherapy using T cells expressing chimeric antigen receptors (CARs) targeting CD19 has produced remarkable clinical outcomes. However, much of the mechanisms of action, such as the development of memory responses and sources of immune cytokines, remain elusive largely due t...
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| 出版年: | EBioMedicine |
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| 主要な著者: | , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Elsevier
2018
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6354733/ https://ncbi.nlm.nih.gov/pubmed/30579863 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebiom.2018.12.013 |
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