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Novel cellular therapies for leukemia: CAR-modified T cells targeted to the CD19 antigen

The ability of immune-competent donor T cells to mediate a beneficial graft-versus-leukemia (GVL) effect was first identified in the setting of allogeneic hematopoietic stem cell transplantation (allo-HSCT) for hematologic malignancies. Unfortunately, with the exception of chronic myelogenous leukem...

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Detalhes bibliográficos
Publicado no:Hematology Am Soc Hematol Educ Program
Main Authors: Brentjens, Renier J., Curran, Kevin J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5536093/
https://ncbi.nlm.nih.gov/pubmed/23233573
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/asheducation-2012.1.143
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