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Engineering strategies to overcome the current roadblocks in CAR T cell therapy
T cells genetically engineered to express chimeric antigen receptors (CARs) have proven — and impressive — therapeutic activity in patients with certain subtypes of B cell leukaemia or lymphoma, with promising efficacy also demonstrated in patients with multiple myeloma. Nevertheless, various barrie...
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| Publicado no: | Nat Rev Clin Oncol |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7223338/ https://ncbi.nlm.nih.gov/pubmed/31848460 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41571-019-0297-y |
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