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Toxicity and management in CAR T-cell therapy
T cells can be genetically modified to target tumors through the expression of a chimeric antigen receptor (CAR). Most notably, CAR T cells have demonstrated clinical efficacy in hematologic malignancies with more modest responses when targeting solid tumors. However, CAR T cells also have the capac...
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| Published in: | Mol Ther Oncolytics |
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| Main Authors: | , , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
Nature Publishing Group
2016
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5008265/ https://ncbi.nlm.nih.gov/pubmed/27626062 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mto.2016.11 |
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