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Driving CAR T-cells forward
The engineered expression of chimeric antigen receptors (CARs) on the surface of T cells enables the redirection of T-cell specificity. Early clinical trials using CAR T cells for the treatment of patients with cancer showed modest results, but the impressive outcomes of several trials of CD19-targe...
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| Veröffentlicht in: | Nat Rev Clin Oncol |
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| Hauptverfasser: | , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2016
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5529102/ https://ncbi.nlm.nih.gov/pubmed/27000958 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nrclinonc.2016.36 |
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