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CAR therapy for hematological cancers: can success seen in the treatment of B-cell acute lymphoblastic leukemia be applied to other hematological malignancies?

Chimeric antigen receptor (CAR) T-cell therapy has recently come into the spotlight due to impressive results in patients with B-cell acute lymphoblastic leukemia. By targeting CD19, a marker expressed most B-cell tumors, as well as normal B cells, CAR T-cell therapy has been investigated as a treat...

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Detalhes bibliográficos
Publicado no:Immunotherapy
Main Authors: Pegram, Hollie J, Smith, Eric L, Rafq, Sarwish, Brentjens, Renier J
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5238709/
https://ncbi.nlm.nih.gov/pubmed/26065479
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2217/imt.15.6
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