A nuclear lamina‐chromatin‐Ran GTPase axis modulates nuclear import and DNA damage signaling

The Ran GTPase regulates nuclear import and export by controlling the assembly state of transport complexes. This involves the direct action of RanGTP, which is generated in the nucleus by the chromatin‐associated nucleotide exchange factor, RCC1. Ran interactions with RCC1 contribute to formation o...

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Publicat a:Aging Cell
Autors principals: Dworak, Natalia, Makosa, Dawid, Chatterjee, Mandovi, Jividen, Kasey, Yang, Chun‐Song, Snow, Chelsi, Simke, William C., Johnson, Isaac G., Kelley, Joshua B., Paschal, Bryce M.
Format: Artigo
Idioma:Inglês
Publicat: John Wiley and Sons Inc. 2018
Matèries:
Original Papers
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6351833/
https://ncbi.nlm.nih.gov/pubmed/30565836
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.12851
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