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Monoclonal Antibodies to NTF2 Inhibit Nuclear Protein Import by Preventing Nuclear Translocation of the GTPase Ran

Nuclear transport factor 2 (NTF2) is a soluble transport protein originally identified by its ability to stimulate nuclear localization signal (NLS)-dependent protein import in digitonin-permeabilized cells. NTF2 has been shown to bind nuclear pore complex proteins and the GDP form of Ran in vitro....

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Autores principales: Steggerda, Susanne M., Black, Ben E., Paschal, Bryce M.
Formato: Artigo
Lenguaje:Inglês
Publicado: The American Society for Cell Biology 2000
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC14804/
https://ncbi.nlm.nih.gov/pubmed/10679025
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