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Monoclonal Antibodies to NTF2 Inhibit Nuclear Protein Import by Preventing Nuclear Translocation of the GTPase Ran

Nuclear transport factor 2 (NTF2) is a soluble transport protein originally identified by its ability to stimulate nuclear localization signal (NLS)-dependent protein import in digitonin-permeabilized cells. NTF2 has been shown to bind nuclear pore complex proteins and the GDP form of Ran in vitro....

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Udgivet i:Mol Biol Cell
Principais autores: Steggerda, Susanne M., Black, Ben E., Paschal, Bryce M.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Cell Biology 2000
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Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC14804/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10679025/
https://ncbi.nlm.nih.govhttps://doi.org/10.1091/mbc.11.2.703
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