A nuclear lamina‐chromatin‐Ran GTPase axis modulates nuclear import and DNA damage signaling

The Ran GTPase regulates nuclear import and export by controlling the assembly state of transport complexes. This involves the direct action of RanGTP, which is generated in the nucleus by the chromatin‐associated nucleotide exchange factor, RCC1. Ran interactions with RCC1 contribute to formation o...

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Enregistré dans:
Détails bibliographiques
Publié dans:Aging Cell
Auteurs principaux: Dworak, Natalia, Makosa, Dawid, Chatterjee, Mandovi, Jividen, Kasey, Yang, Chun‐Song, Snow, Chelsi, Simke, William C., Johnson, Isaac G., Kelley, Joshua B., Paschal, Bryce M.
Format: Artigo
Langue:Inglês
Publié: John Wiley and Sons Inc. 2018
Sujets:
Original Papers
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6351833/
https://ncbi.nlm.nih.gov/pubmed/30565836
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.12851
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