A nuclear lamina‐chromatin‐Ran GTPase axis modulates nuclear import and DNA damage signaling

The Ran GTPase regulates nuclear import and export by controlling the assembly state of transport complexes. This involves the direct action of RanGTP, which is generated in the nucleus by the chromatin‐associated nucleotide exchange factor, RCC1. Ran interactions with RCC1 contribute to formation o...

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Detalhes bibliográficos
Publicado no:Aging Cell
Main Authors: Dworak, Natalia, Makosa, Dawid, Chatterjee, Mandovi, Jividen, Kasey, Yang, Chun‐Song, Snow, Chelsi, Simke, William C., Johnson, Isaac G., Kelley, Joshua B., Paschal, Bryce M.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2018
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Original Papers
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6351833/
https://ncbi.nlm.nih.gov/pubmed/30565836
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.12851
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