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Disruption of the Ran System by Cysteine Oxidation of the Nucleotide Exchange Factor RCC1
Transport regulation by the Ran GTPase requires its nuclear localization and GTP loading by the chromatin-associated exchange factor RCC1. These reactions generate Ran protein and Ran nucleotide gradients between the nucleus and the cytoplasm. Cellular stress disrupts the Ran gradients, but the spec...
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| Publicado en: | Mol Cell Biol |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
American Society for Microbiology
2015
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4285427/ https://ncbi.nlm.nih.gov/pubmed/25452301 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01133-14 |
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