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Cell Cycle-Dependent Binding Modes of the Ran Exchange Factor RCC1 to Chromatin

The formation of an activity gradient of the small G-protein Ran around chromatin depends on the differential partitioning of the opposing enzyme activities of the Ran guanine nucleotide exchange factor RCC1 that resides on chromatin, and the cytoplasmic Ran GTPase activating protein RanGAP. We stud...

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Detalhes bibliográficos
Main Authors: Bierbaum, Martin, Bastiaens, Philippe I.H.
Formato: Artigo
Idioma:Inglês
Publicado em: The Biophysical Society 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3627872/
https://ncbi.nlm.nih.gov/pubmed/23601311
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2013.03.024
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