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Cell Cycle-Dependent Binding Modes of the Ran Exchange Factor RCC1 to Chromatin

The formation of an activity gradient of the small G-protein Ran around chromatin depends on the differential partitioning of the opposing enzyme activities of the Ran guanine nucleotide exchange factor RCC1 that resides on chromatin, and the cytoplasmic Ran GTPase activating protein RanGAP. We stud...

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Autors principals: Bierbaum, Martin, Bastiaens, Philippe I.H.
Format: Artigo
Idioma:Inglês
Publicat: The Biophysical Society 2013
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3627872/
https://ncbi.nlm.nih.gov/pubmed/23601311
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2013.03.024
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