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Cryo-EM structures of the archaeal PAN-proteasome reveal an around-the-ring ATPase cycle

Proteasomes occur in all three domains of life, and are the principal molecular machines for the regulated degradation of intracellular proteins. They play key roles in the maintenance of protein homeostasis, and control vital cellular processes. While the eukaryotic 26S proteasome is extensively ch...

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Detalles Bibliográficos
Publicado en:Proc Natl Acad Sci U S A
Main Authors: Majumder, Parijat, Rudack, Till, Beck, Florian, Danev, Radostin, Pfeifer, Günter, Nagy, István, Baumeister, Wolfgang
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 2019
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6329974/
https://ncbi.nlm.nih.gov/pubmed/30559193
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1817752116
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