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Interactions of PAN's C-termini with archaeal 20S proteasome and implications for the eukaryotic proteasome–ATPase interactions

Protein degradation in the 20S proteasome is regulated in eukaryotes by the 19S ATPase complex and in archaea by the homologous PAN ATPase ring complex. Subunits of these hexameric ATPases contain on their C-termini a conserved hydrophobic-tyrosine-X (HbYX) motif that docks into pockets in the 20S t...

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Bibliografiske detaljer
Main Authors: Yu, Yadong, Smith, David M, Kim, Ho Min, Rodriguez, Victor, Goldberg, Alfred L, Cheng, Yifan
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2010
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2830694/
https://ncbi.nlm.nih.gov/pubmed/20019667
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2009.382
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