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Cryo-EM structures of the archaeal PAN-proteasome reveal an around-the-ring ATPase cycle

Proteasomes occur in all three domains of life, and are the principal molecular machines for the regulated degradation of intracellular proteins. They play key roles in the maintenance of protein homeostasis, and control vital cellular processes. While the eukaryotic 26S proteasome is extensively ch...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Majumder, Parijat, Rudack, Till, Beck, Florian, Danev, Radostin, Pfeifer, Günter, Nagy, István, Baumeister, Wolfgang
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6329974/
https://ncbi.nlm.nih.gov/pubmed/30559193
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1817752116
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